Great news! Our paper submitted to the Conference in Artificial Intelligence in Medicine hosted in Murcia, Spain, has been accepted! The paper is available at the reference below: Ludwig Krippahl, Fábio Madeira and Pedro Barahona. 2013. Constraining Protein Docking with Coevolution Data for Medical Research. Proceedings of the 14th Conference…
I recently move to Dundee, the 4rd biggest city in Scotland, to do my PhD in Life Sciences at the University of Dundee. So far I am enjoying the views so much! Dundee panorama. Photo by David Martin, 2006. …
BibYAML stands for Bibliographic YAML, and aims to be a new standard for managing, formatting and storing bibliographies. Inheriting the advantages of BibTeX and YAML, it provides human and machine readable bibliographic records that can populate your database and documents. Let’s see how it works! As a simple tool I…
Hello folks! After reading a very nice post about Jekyll and GitHub Pages by Kevin Sornberger, I decided to build a new home using the same approach. This way I can get the fun of it more quickly and I can design later. What will be the scope of this…
A long-standing goal in Bioinformatics has been to predict protein structure from sequence. One aspect that obviously matters is amino acids’ physico-chemical properties. Proteins are quite compact in structure, and the different residues pack together in a way that is almost space filling (search for shape complementarity). The volume occupied…
“Nothing in bioinformatics makes sense except in the light of evolution”, by Paul G. Higgs and Teresa K. Attwood, in adaptation of the famous Theodosius Dobzhansky’s remark. Have you notice that the most fundamental procedures in bioinformatics rely on sequence search and alignment? When amino acid sequences are aligned, scoring…
On a recent paper, “Structural insights into multi-protein communication systems” PubMed, Christine Orengo and James Whisstock discuss how individual protein components participate in complex multi-protein machines, achieving specific functional outcomes. They start by addressing the importance of the protein components at the ‘individual level’. Structural information is crucial to protein…